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カタログ番号	製品名	別名	ターゲット
T3048	10058-F4	c-Myc Inhibitor	c-Myc , Autophagy
	10058-F4 (c-Myc Inhibitor) is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; induces cell-cycle arrest and apoptosis.		c-Myc , Autophagy
T72040	c-Myc inhibitor 7
	C-Myc Inhibitor 7, serving as both a c-Myc inhibitor and a multi-target protein degrader, effectively degrades proteins c-MYC, CK1α, GSPT1, and IKZF1/2/3 across various tumor cell types. It holds potential for research i...
T9061	EN4	EN4 MYC inhibitor	c-Myc
	EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional activity, downregulates MYC targets, an...		c-Myc
T3686	10074-G5		c-Myc , Autophagy
	10074-G5 is an inhibitor of c-Myc-Max dimerization.		c-Myc , Autophagy
T4252	ML327		c-Myc , Autophagy
	ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).		c-Myc , Autophagy
T15665	KJ Pyr 9		c-Myc , Autophagy
	KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).		c-Myc , Autophagy
T9628	10074-A4		c-Myc
	10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from that of a non-binding ligand.		c-Myc
T4367	Mycro 3	Mycro-3	c-Myc , Autophagy
	Mycro 3 is potent and selective for c-Myc in whole cell assays.		c-Myc , Autophagy
T12132	MYCi361	NUCC-0196361	c-Myc
	MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).		c-Myc
T9033	BTYNB	MDK6620,BTYNB IMP1 Inhibitor	Others , c-Myc , NF-κB
	BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa ...		Others , c-Myc , NF-κB
T12134	MYCMI-6	NSC354961	Apoptosis , c-Myc
	MYCMI-6 (NSC-354961) is a potent and selective inhibitor of endogenous MYC:MAX protein interactions，reduces proliferation and induces massive apoptosis in tumor tissue from a MYC-driven xenograft tumor model without seve...		Apoptosis , c-Myc
T60019	VPC-70063	Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-	Apoptosis , PARP , c-Myc
	VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with an IC50 of 8.9 μM and Myc-Max/UBE2C do...		Apoptosis , PARP , c-Myc
T20533	NNK	Nicotine-derived nitrosamine ketone	Lipoxygenase
	NNK (Nicotine-derived nitrosamine ketone) is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor.		Lipoxygenase
T10352	APTO-253	LOR-253,LT-253	Apoptosis , c-Myc , KLF
	APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the K...		Apoptosis , c-Myc , KLF
T75239	c-Myc inhibitor 10
	C-Myc Inhibitor 10 (compound 17), exhibiting enhanced cellular potency, benefits from increased permeability due to the methylation of the morpholine nitrogen [1].
T11284	FIDAS-3		Others , Wnt/beta-catenin , Methionine Adenosyltransferase (MAT)
	FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for ...
T11285	FIDAS-5		Others
	FIDAS-5, a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM, competitively inhibits S-adenosylmethionine (SAM) binding to MAT2A. It exhibits anticancer activities.		Others
T74460	c-Myc inhibitor 5
	c-Myc Inhibitor 5 (DA3) is a fluorescent bispurine compound with a long-chain bridge that selectively binds to the c-MYC G-quadruplex, exhibiting a dissociation constant (K D) of 16 μM. Unlike other G4-driven oncogenes, ...
T72619	c-Myc inhibitor 8
	C-Myc Inhibitor 8 is an effective compound for cancer research, inhibiting cell viability across a range of cancer types and demonstrating growth suppression in human prostate and lung cancers within mouse models. This i...
T79439	c-Myc inhibitor 12		c-Myc
	Compound 67h, also known as c-Myc inhibitor 12, is a potent inhibitor of c-Myc, exhibiting a pEC50 value of 6.4 [1].		c-Myc
T63359	c-Myc inhibitor 4
	c-Myc inhibitor 4 is a potent, orally active c-Myc-reducing compound. c-Myc is an important proto-oncogene, which is closely associated with the development of many tumors.
T72620	c-Myc inhibitor 9
	c-Myc Inhibitor 9 (Compound 332) is an effective c-Myc inhibitor, exhibiting a logEC50 of ≥6, and demonstrating significant tumor growth inhibition in nude mouse models. This compound is utilized in cancer research.
T79438	c-Myc inhibitor 11		c-Myc
	c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in rat pharmacokinetic assays, making it suitable for cancer researc...		c-Myc
T10760	Ceramides Mixture		Telomerase
	Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activ...		Telomerase
T9093	NY2267	Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester	c-Myc
	NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester) is a disruptor of Myc-Max interaction, with an IC50 of 36...		c-Myc
T10765	Eragidomide	CC-90009,Cereblon modulator 1	Apoptosis , Ligand for E3 Ligase , Molecular Glues
	Eragidomide (CC-90009; Cereblon modulator 1) is a cereblon (CRBN) E3 ligase modulator. Eragidomide specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.		Apoptosis , Ligand for E3 Ligase , Molecular Glues
T6203	Saxagliptin	BMS-477118,Onglyza	Proteasome , DPP-4
	Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.		Proteasome , DPP-4
T6010	Idarubicin hydrochloride	Idamycin,4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl,4-Demethoxydaunorubicin hydrochloride,Idarubicin HCl,Zavedos	Topoisomerase , Antibacterial , Autophagy , Antifungal
	Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).		Topoisomerase , Antibacterial , Autophagy , Antifungal
T0178	Saxagliptin hydrate	Onglyza hydrate,BMS-477118 hydrate	Proteasome , DPP-4
	Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).		Proteasome , DPP-4
T28543	RK-9123016	RK9123016,RK 9123016	Sirtuin
	RK-9123016 is a SIRT2 inhibitor. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer ce...		Sirtuin
T15137	DK419		Wnt/beta-catenin , AMPK
	DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM. DK419 decreases protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin.It also induces production of pAMPK.		Wnt/beta-catenin , AMPK
T74794	USP28-IN-4		DUB
	USP28-IN-4 is a potent USP28 inhibitor with an IC50 value of 0.04 μM against USP28. USP28-IN-4 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3 and UCHL5. USP28-IN-4 is cytotoxic to human colorect...		DUB
T74793	USP28-IN-3		DUB
	USP28-IN-3 is a highly selective USP28 inhibitor with an IC50 value of 0.1 μM against USP28.USP28-IN-3 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3, and UCHL5.USP28-IN-3 is cytotoxic to human ...		DUB
T3708	BP-1-102		STAT
	BP-1-102 is an orally active, effective and specific STAT3 inhibitor. BP-1-102 binds Stat3 (Kd: 504 nM), then blocks Stat3-phosphotyrosine (pTyr) peptide interactions and Stat3 activation (4-6.8 μM), and selectively inhi...		STAT
T10717	Inobrodib	CBP-IN-1	Epigenetic Reader Domain
	Inobrodib (CBP-IN-1) is a potent inhibitor of p300/CBP bromodomain.		Epigenetic Reader Domain
T11783	KSI-3716		c-Myc
	KSI-3716 is an inhibitor of c-Myc.		c-Myc
T11698	IZCZ-3		Others
	IZCZ-3,antitumor activity. is a potent c-MYC transcription inhibitor.		Others
T69464	Mycro2
	Mycro2 is an inhibitor of the protein-protein interactions between the bHLHZip proteins c-Myc and Max.
T69465	Mycro1
	Mycro1 is an inhibitor of the protein-protein interactions between the bHLHZip proteins c-Myc and Max.
T23872	Cellocidin	NSC65381,NSC# 65381,NSC-65381,NSC#65381,NSC 65381
	Cellocidin is a potent gammaherpesvirus-associated B-lymphomas growth inhibitor. It acts through the activation of both the NF-κB and c-Myc-mediated signaling pathways.
T24548	NSC10010 hydrochloride	NSC#10010,NSC 10010,NSC# 10010,NSC#-10010,NSC-10010
	NSC10010 hydrochloride is an effective growth inhibitor for gammaherpesvirus-associated B-lymphomas. It acts through activation of both the NF-κB and c-Myc-mediated signaling pathways.
T16721	Ralimetinib	LY2228820	Others
	Ralimetinib selectively inhibits phosphorylation of MK2 (Thr334) and has no effect on phosphorylation of p38α MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc. Ralimetinib is an effective and selective, ATP-competitive inhibitor...		Others
T40419	IRES-C11	IRES-C11	c-Myc
	IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans...		c-Myc
T79872	M-Se3		c-Myc
	m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].		c-Myc
T72829	β-catenin-IN-4
	β-Catenin-IN-4 is a β-catenin inhibitor characterized by a K_i value of 0.64 μM. This compound effectively lowers the protein expression levels of cyclin D1 and c-Myc.
T63767	P300 bromodomain-IN-1
	P300 bromodomain-IN-1 is a potent inhibitor of p300 (EP300) bromodomain (IC50: 49 nM). p300 bromodomain-IN-1 blocks c-Myc expression and induces cell cycle arrest at G1/G0 phase and apoptosis in OPM-2 cells. apoptosis).
T78846	EP12		Apoptosis
	EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by disrupting the NF-κB signaling pathway, effectively inhibiting mult...		Apoptosis
T79354	CDK9-IN-24		CDK
	CDK9-IN-24 (compound 21a) is a potent and selective inhibitor of CDK9 that exhibits a pronounced inhibitory impact on tumor proliferation. It impedes cell growth and triggers apoptosis via the downregulation of Mcl-1 and...		CDK
T61327	BRD4 Inhibitor-15
	BRD4 Inhibitor-15 (compound 13) is a highly potent and specific inhibitor of BRD4, effectively inhibiting it with an IC50 of 18 nM. By regulating the Bcl-2/Bax proteins and activating the caspase-3 signaling pathway, BRD...
T74899	GXH-II-052
	GXH-II-052 is a potent bivalent inhibitor targeting the bromodomain and extraterminal domain (BET). It exhibits significant binding affinity to various BET proteins, including BRD4-1, BRD4-2, BRD4-T, BRDT-1, BRDT-2, and ...

Compounds

10058-F4

T3048

Synonym: c-Myc Inhibitor

Target: c-Myc, Autophagy

Synonym: EN4 MYC inhibitor

Target: c-Myc, Autophagy

ML327

T4252

Synonym:

Target: c-Myc, Autophagy

KJ Pyr 9

T15665

Synonym:

Target: c-Myc, Autophagy

Target: c-Myc, Autophagy

MYCi361

T12132

Synonym: NUCC-0196361

Target: c-Myc

BTYNB

T9033

Synonym: MDK6620,BTYNB IMP1 Inhibitor

Target: Others, c-Myc, NF-κB

MYCMI-6

T12134

Synonym: NSC354961

Target: Apoptosis, c-Myc

VPC-70063

T60019

Synonym: Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-

Target: Apoptosis, PARP, c-Myc

NNK

T20533

Synonym: Nicotine-derived nitrosamine ketone

Target: Lipoxygenase

APTO-253

T10352

Synonym: LOR-253,LT-253

Target: Apoptosis, c-Myc, KLF

Target: Others, Wnt/beta-catenin, Methionine Adenosyltransferase (MAT)

Synonym: Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester

Target: c-Myc

Eragidomide

T10765

Synonym: CC-90009,Cereblon modulator 1

Target: Apoptosis, Ligand for E3 Ligase, Molecular Glues

Saxagliptin

T6203

Synonym: BMS-477118,Onglyza

Target: Proteasome, DPP-4

Idarubicin hydrochloride

T6010

Synonym: Idamycin,4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl,4-Demethoxydaunorubicin hydrochloride,Idarubicin HCl,Zavedos

Target: Topoisomerase, Antibacterial, Autophagy, Antifungal

Saxagliptin hydrate

T0178

Synonym: Onglyza hydrate,BMS-477118 hydrate

Target: Proteasome, DPP-4

RK-9123016

T28543

Synonym: RK9123016,RK 9123016

Target: Wnt/beta-catenin, AMPK

Target: Epigenetic Reader Domain

Synonym: NSC65381,NSC# 65381,NSC-65381,NSC#65381,NSC 65381

Target:

NSC10010 hydrochloride

T24548

Synonym: NSC#10010,NSC 10010,NSC# 10010,NSC#-10010,NSC-10010

P300 bromodomain-IN-1

カタログ番号	製品名	別名	ターゲット
TN1892	Lusianthridin		Others , c-Myc
	Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signali...		Others , c-Myc
T21065	Artemisitene		Others
	Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinin B, Artemisitene, Artemisini...		Others
T3673	Mollugin	Rubimaillin	HER , JAK
	Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...		HER , JAK
T4S1173	Agrimol B		Sirtuin , PPAR
	1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.		Sirtuin , PPAR
TN6508	Trachelogenin	(-)-Trachelogenin	Virus Protease , c-Myc , HCV Protease , Wnt/beta-catenin
	Trachelogenin ((-)-Trachelogenin), isolated from Combretum fruticosum, is an HCV entry inhibitor with anti-proliferative effects. Its mechanism is related to affecting the phosphorylation of key proteins such as β-Cateni...		Virus Protease , c-Myc , HCV Protease , Wnt/beta-catenin
TMA1743	Ergosterol peroxide		ERK , VEGFR , p38 MAPK , Wnt/beta-catenin , Akt , JAK , CDK , JNK , STAT , Antifection
	Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Foxo3a activity by inhibiting pAKT and c-Myc and activating pr...

天然物製品

Lusianthridin

TN1892

Synonym:

Target: Others, c-Myc

Target: Sirtuin, PPAR

Trachelogenin

TN6508

Synonym: (-)-Trachelogenin

Target: Virus Protease, c-Myc, HCV Protease, Wnt/beta-catenin

Ergosterol peroxide

TMA1743

Synonym:

Target: ERK, VEGFR, p38 MAPK, Wnt/beta-catenin, Akt, JAK, CDK, JNK, STAT, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-00478	DIT33 Protein, Dirofilaria immitis, Recombinant (His & Myc)	Dirofilaria immitis	E. coli
	Aspartyl protease inhibitor. DIT33 Protein, Dirofilaria immitis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.0 kDa and the accession...
TMPH-00155	Barstar Protein, Bacillus amyloliquefaciens, Recombinant (His & Myc)	Bacillus amyloliquefaciens	E. coli
	Inhibitor of the ribonuclease barnase. Forms a one-to-one non-covalent complex. Barstar Protein, Bacillus amyloliquefaciens, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. ...
TMPH-02436	5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc)	Cynomolgus	E. coli
	May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) is expresse...
TMPH-02437	5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc)	Cynomolgus	HEK293 Cells
	May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) is expressed in HEK2...
TMPH-03204	GHR Protein, Rabbit, Recombinant (His & Myc)	Rabbit	E. coli
	Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon...
TMPH-02898	SPINK2 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defe...
TMPH-01335	FGF-5 Protein, Human, Recombinant (GST & His & Myc)	Human	E. coli
	Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression fro...
TMPH-00897	Human adenovirus C serotype 2 Early E3 18.5 kDa glycoprotein (His & Myc)	HAdV-2	E. coli
	Binds and retains class I heavy chains in the endoplasmic reticulum during the early period of virus infection, thereby impairing their transport to the cell surface. Also delays the expression of class I alleles that it...
TMPH-03685	Varicella-zoster virus (strain Oka vaccine) glycoprotein L/gL Protein (His & Myc)	HHV-3	E. coli
	The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form...
TMPH-00227	Beta-casein Protein, Bovine, Recombinant (His & Myc)	Bovine	E. coli
	Important role in determination of the surface properties of the casein micelles.; Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It als...
TMPH-03684	Varicella-zoster virus (strain Dumas) glycoprotein L/gL Protein (His & Myc)	HHV-3	E. coli
	The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form...
TMPK-01456	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01451	HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01450	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...